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Estramustine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Estramustine图片
CAS NO:2998-57-4
包装与价格:
包装价格(元)
250mg电议
1g电议

产品介绍
Estramustine 是一种抗肿瘤剂。Estramustine 通过与微管蛋白 1 (tubulin 1)结合来解聚微管,具有抗有丝分裂活性,对 DU 145 细胞有丝分裂的 IC50 大约为 16 μM。Estramustine 在前列腺肿瘤异种移植模型中阻断前列腺肿瘤细胞有丝分裂。
Cas No.2998-57-4
分子式C23H31Cl2NO3
分子量440.4
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Estramustine is an antineoplastic agent. Estramustine depolymerizes microtnbules by binding totubulin 1, exhibits antimitotic activity with anIC50value of ~16 μM for mitosis of DU 145 cells. Estramustine blocks cells at mitosis in prostate tumor xenografts[1].

[1]. DahllÖf B, et al. Estramustine depolymerizes microtubules by binding to tubulin. Cancer Res. 1993 Oct 1;53(19):4573-81.