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Podophyllotoxone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Podophyllotoxone图片
CAS NO:477-49-6
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Podophyllotoxone 是从八角莲根中分离得到的,具有抗癌活性。Podophyllotoxone 能够抑制 tubulin 微管蛋白聚合。
Cas No.477-49-6
别名鬼臼脂毒酮
分子式C22H20O8
分子量412.39
溶解度DMSO : 100 mg/mL (242.49 mM; Need ultrasonic)
储存条件4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization[1].

Podophyllotoxone inhibits human prostate cancer cells PC3 and DU145 growth with IC50 values of 14.7 and 20.6 µM[1].

[1]. Juan Li , et al. Absolute Configuration of Podophyllotoxone and Its Inhibitory Activity Against Human Prostate Cancer Cells. Chin J Nat Med. 2015 Jan;13(1):59-64.