您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Nortriptyline
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Nortriptyline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nortriptyline图片
CAS NO:72-69-5
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
Nortriptyline (Desmethylamitriptyline) 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢产物,用于缓解抑郁症症状。Nortriptyline 是有效自噬 (autophagy) 抑制剂。
Cas No.72-69-5
别名去甲替林,Desmethylamitriptyline; Desitriptilina
分子式C19H21N
分子量263.38
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nortriptyline (Desmethylamitriptyline), the main active metabolite of Amitriptyline, is a tricyclic antidepressant used to relieve the symptoms of depression. Nortriptyline is a potent autophagy inhibitor[1][2].

[1]. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. In: Pratt VM, Scott SA, Pirmohamed M, et al., eds. Medical Genetics Summaries. Bethesda (MD): National Center for Biotechnology Information (US); March 23, 2017.
[2]. Petrosyan E, et al. Repurposing Autophagy Regulators in Brain Tumors [published online ahead of print, 2022 Feb 18]. Int J Cancer. 2022;10.1002/ijc.33965.