| 包装 | 价格(元) |
| 100mg | 电议 |
| 500mg | 电议 |
| 1 g | 电议 |
| Canonical SMILES | OC[C@H](N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O)=O.CC(O)=O |
| 分子式 | C28H53N7O8• XC2H4O2 |
| 分子量 | 615.8 |
| 溶解度 | DMF: insol,DMSO: insol,Ethanol: insol,PBS (pH 7.2): 2 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SIKVAV is a laminin α1-derived peptide.1It binds to α3, α6, and β1 integrins and induces adhesion of CAC2 adenoid cystic carcinoma cells when used at a concentration of 1 µg/ml. SIKVAV (100 µg/ml) stimulates the proliferation and migration of primary mouse fibroblasts, as well as induces the secretion of EGF, VEGF, TGF-β, and FGF in the same cells.2Topical administration of a chitosan hydrogel containing SIKVAV promotes wound healing and angiogenesis in mice. 1.Freitas, V.M., Vilas-Boas, V.F., Pimenta, D.C., et al.SIKVAV, a laminin α1-derived peptide, interacts with integrins and increases protease activity of a human salivary gland adenoid cystic carcinoma cell line through the ERK 1/2 signaling pathwayAm. J. Pathol.171(1)124-138(2007) 2.Chen, X., Zhang, M., Chen, S., et al.Peptide-modified chitosan hydrogels accelerate skin wound healing by promoting fibroblast proliferation, migration, and secretionCell Transplant.26(8)1331-1340(2017) |
m.cnreagent.com