CAS NO: | 1241280-25-0 |
包装 | 价格(元) |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Cas No. | 1241280-25-0 | ||||||||||||||||
别名 | GPR183 antagonist-1 | ||||||||||||||||
分子式 | C19H19F3N2O2 | ||||||||||||||||
分子量 | 364.36 | ||||||||||||||||
溶解度 | DMSO : 100 mg/mL (274.45 mM; ultrasonic and warming and heat to 60°C) | ||||||||||||||||
储存条件 | Store at -20°C | ||||||||||||||||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. | ||||||||||||||||
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request | ||||||||||||||||
产品描述 | IC50: 28.5 nM (GPR183)[1] SAE-14 (compound SAE-14) is a potent, specificGPR183antagonist with anIC50value of 28.5 nM, can antagonize 7α, 25-OHC-induced calcium mobilization withIC50value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice[1]. SAE-14 (compound SAE-14) can able to antagonize 7α, 25-OHC-induced calcium mobilization with an IC50value below 50 nM[1]. Cell Viability Assay[1]
SAE-14 (compound SAE-14) (i.th.; 2.9 µM; once) can reverse nerve injury-induced allodynia in mice[1].
|