| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Canonical SMILES | CC(N[C@@H](CO)C(N[C@H](CC(O)=O)C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(O)=O)=O)=O)=O)=O.CC(O)=O |
| 分子式 | C20H33N5O9• XC2H4O2 |
| 分子量 | 487.5 |
| 溶解度 | Water: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Goralatide is a tetrapeptide regulator of hematopoiesis.1It decreases the proportion of mouse high proliferative potential colony forming cells (HPP-CFCs) in S phase when cultured using regenerating femoral marrow conditioned medium at a concentration of 1 ng/ml. Goralatide (4 µg/kg twice per day) reduces decreases in the number of HPP-CFCs, burst-forming unit erythroid (BFU-E) cells, and colony forming unit granulocyte-macrophages (CFU-GMs) induced by 5-fluorouracil in mice.2It also reduces mortality induced by doxorubicin in mice.3 1.Robinson, S., Lenfant, M., Wdzieczak-Bakala, J., et al.The molecular specificity of action of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) in the control of hematopoietic stem cell proliferationStem Cells11(5)422-427(1993) 2.Aidoudi, S., Guigon, M., Lebeurier, I., et al.In vivo effect of platelet factor 4 (PF4) and tetrapeptide AcSDKP on haemopoiesis of mice treated with 5-fluorouracilBr. J. Haematol.94(3)443-448(1996) 3.MassÉ, A., Ramirez, L.H., Bindoula, G., et al.The tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (Goralatide) protects from doxorubicin-induced toxicity: Improvement in mice survival and protection of bone marrow stem cells and progenitorsBlood91(2)441-449(1998) |
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