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Dimethindene maleate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dimethindene maleate图片
CAS NO:3614-69-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Dimethindene maleate 是一种选择性的 histamine H1 拮抗剂,具有抗组胺效应。Dimethindene maleate 可用于过敏性反应的研究。
Cas No.3614-69-5
分子式C24H28N2O4
分子量408.49
储存条件Store at -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dimethindene maleate is a selectivehistamine H1antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions[1][2][3].

Dimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive Kcurrents in a concentration-dependent and reversible manner with an IC50value of 29.5 μM[2].
Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive Kcurrents with an IC50value of 49 μM[2].

Dimethindene maleate (0.25 mg; i.p. once) affects wound healing in mice[1].

Animal Model:C57BL/6 mice with wound healing[1]
Dosage:0.25 mg
Administration:Intraperitoneal injection; 0.25 mg once
Result:Significantly delayed skin wound and only showed wound closure impairment in the initial phase wound healing.