CAS NO: | 2268720-62-1 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
Cas No. | 2268720-62-1 |
分子式 | C19H15Br2N5O2S2 |
分子量 | 569.29 |
溶解度 | DMSO : 125 mg/mL (219.57 mM; ultrasonic and warming and heat to 60°C) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1]. [1]. Wu JW, et al. Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorg Med Chem Lett. 2019 Feb 1;29(3):383-388. |