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URAT1 inhibitor 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
URAT1 inhibitor 1图片
CAS NO:2268720-62-1
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
URAT1 inhibitor 1 (1g) 是尿酸转运体 1(URAT1) 的一种抑制剂,其抑制尿酸转运体 1 (URAT1) 的 IC50 值为的 32 nM。URAT1 inhibitor 1 有望用于高尿酸血症痛风的研究。
Cas No.2268720-62-1
分子式C19H15Br2N5O2S2
分子量569.29
溶解度DMSO : 125 mg/mL (219.57 mM; ultrasonic and warming and heat to 60°C)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout[1].

[1]. Wu JW, et al. Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout. Bioorg Med Chem Lett. 2019 Feb 1;29(3):383-388.