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Etripamil
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Etripamil图片
CAS NO:1593673-23-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Etripamil (MSP-2017) 是一种短效的、L-型 钙通道 拮抗剂,能用于阵发性室上性心动过速 (PSVT) 的研究。Etripamil (MSP-2017) 通过钙离子慢通道抑制钙离子内流,从而减缓房室结传导,延长房室结不应期。
Cas No.1593673-23-4
别名MSP-2017; (-)-MSP-2017
分子式C27H36N2O4
分子量452.59
溶解度Ethanol : 120 mg/mL (265.14 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist, can be used for the research of Paroxysmal Supraventricular Tachycardia (PSVT). Etripamil (MSP-2017) slows atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells[1][2].

[1]. Stambler BS, et al. Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. J Am Coll Cardiol. 2018 Jul 31;72(5):489-497.
[2]. Milestone Pharmaceuticals Announces USAN Approval of Generic Name "Etripamil" for its Phase 2 Clinical Development Product for the Treatment of Paroxysmal Supraventricular Tachycardia.