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Angiotensin 1/2(1-7)amide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Angiotensin 1/2(1-7)amide图片
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍

Vasoconstrictor

别名H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide
Canonical SMILESO=C(N)[C@@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC)=O)CCCNC(N)=N)=O)C)=O)CC2=CC=C(O)C=C2)=O)[C@@H](C)CC)=O)CC3=CNC=N3)=O)CCC1
分子式C41H63N13O10
分子量898.02
溶解度≥ 89.8mg/mL in DMSO
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Angiotensin I/II (1-7) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide) is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse.
Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe | His-Leu) is an octapeptide that is converted from Angiotensin I (AI) through the removal of two C-terminal residues by angiotensin-converting enzyme (ACE), primarily by ACE within the lung (but also those present in endothelial and kidney epithelial cells). Ang-(1–7) is an endogenous peptide fragment that can be produced from Ang I or Ang II via endo- or carboxy-peptidases respectively. [1]
Angiotensin I/II (1-7) amide is an amide derivative of angiotensin II that is a powerful vasoconstrictor and vasopressor, and is used in the treatment of certain hypotensive states. Angiotensin I/II (1-7) amide is usually administered by slow intravenous infusion, and sometimes intramuscularly or subcutaneously.

References:
1. Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45.