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Sugammadex
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sugammadex图片
CAS NO:343306-71-8
包装与价格:
包装价格(元)
50mg电议
250mg电议

产品介绍
Sugammadex 是一种合成的 γ- 环糊精衍生物,可作为神经肌肉阻滞 (neuromuscular block) 的逆转剂。Sugammadex 在缺血再灌注损伤中具有肾保护作用
Cas No.343306-71-8
别名Org25969 free acid
分子式C72H112O48S8
分子量2002.15
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sugammadex is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent forneuromuscular block. Sugammadex shows nephroprotective effect in ischemia-reperfusion injury[1][2].

Sugammadex (100 mg/kg, IV, once) has a nephroprotective effect when given at the beginning of reperfusion after one hour of ischemic condition on rats[2].

[1]. de Boer HD, et al. Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey. Br J Anaesth. 2006 Apr;96(4):473-9. Epub 2006 Feb 7.
[2]. Tercan M, Y?lmaz ?nal F, Seneldir H, Kocoglu H. Nephroprotective Efficacy of Sugammadex in Ischemia-Reperfusion Injury: An Experimental Study in a Rat Model. Cureus. 2021 Jun 17;13(6):e15726.