您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Atrial Natriuretic Peptide(ANP)(1-28),rat TFA
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Atrial Natriuretic Peptide(ANP)(1-28),rat TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Atrial Natriuretic Peptide(ANP)(1-28),rat TFA图片
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
Atrial Natriuretic Peptide (ANP) (1-28), rat (TFA) 是心房利钠肽 (ANP) 在大鼠中的主要循环形式,强效抑制血管紧张素 II (Ang II)-刺激的内皮素-1 (endothelin-1) 分泌。
别名Atrial natriuretic factor (1-28) (rat) TFA
分子式C130H206N45F3O41S2
分子量3176.43
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Atrial Natriuretic Peptide (ANP) (1-28), rat (TFA) is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner. Endothelin-1[1]

Rat ANP (1-28) and rat BNP-45, which are the respective major circulating forms of ANP and BNP in rats, potently inhibited Ang II-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (5-25) is less effective that Rat ANP(1-28) with respect to inhibiting immunoreactive (ir)-endothelin-1 secretion and increasing cellular cyclic GMP. Rat ANP (1-28) inhibits the secretion of ir-endothelin-1 in a concentration-dependent manner between 0.01 and 1 μM[1].

[1]. Kohno M, et al. Angiotensin II stimulates endothelin-1 secretion in cultured rat mesangial cells. Kidney Int. 1992 Oct;42(4):860-6.