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Acid Ceramidase-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Acid Ceramidase-IN-1图片
CAS NO:2415225-30-6
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
Acid Ceramidase-IN-1 是一种有效的口服生物利用度酸性神经酰胺酶 (AC, ASAH-1) 抑制剂 (hAC IC50=0.166 μM)。Acid Ceramidase-IN-1 对小鼠具有良好的脑渗透性。
Cas No.2415225-30-6
分子式C18H25N3O3
分子量331.41
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice[1].

[1]. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664.