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R-(+)-Mono-desmethylsibutramine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
R-(+)-Mono-desmethylsibutramine图片
CAS NO:229639-54-7
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
R-(+)-Mono-desmethylsibutramine是Mono-desmethylsibutramine的R对映体。
Cas No.229639-54-7
分子式C16H24ClN
分子量265.82
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

R-(+)-Mono-desmethylsibutramine is the R enantiomer of Mono-desmethylsibutramine.

Sibutramine, a monoamine reuptake inhibitor, is used as a racemate, for the treatment of obesity. It is converted in vivo mainly to two desmethyl active metabolites, mono-desmethylsibutramine (MDS) and di-desmethylsibutramine (DDS) [1].

[1]. Bae K, et al. Analysis of enantiomers of sibutramine and its metabolites in rat plasma by liquid chromatography-mass spectrometry using a chiral stationary-phase column. J Pharm Biomed Anal. 2009 Sep 8;50(2):267-70.