(±)-肠内酯是一种生物活性酚类代谢物，被称为哺乳动物木脂素，来源于膳食木脂素。 (±)-Enterolactone 具有雌激素特性和抗乳腺癌活性。 (±)-Enterolactone 是一种放射增敏剂，可通过受损的 DNA 修复和增加的细胞凋亡作用于人类乳腺癌细胞系。
| Cas No. | 78473-71-9 |
| 别名 | 肠内酯 |
| Canonical SMILES | OC1=CC(C[C@@H]([C@H](CC2=CC=CC(O)=C2)CO3)C3=O)=CC=C1 |
| 分子式 | C18H18O4 |
| 分子量 | 298.3 |
| 溶解度 | DMF: 30mg/mL,DMSO: 30mg/mL,Ethanol: miscible,Ethanol:PBS (pH 7.2) (1:5): 100 µ g/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 文献引用 | |
| 产品描述 | Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets. Enterolactone is an enterobacterial breakdown product of plant lignans that is absorbed and can be measured in human serum. Enterolactone and other lignans and phytoestrogens have been associated with a reduced risk of acute coronary events, hormone-dependent cancers, and possibly osteoporosis. Recent observations have shown an inverse association between serum enterolactone levels and serum isoprostane levels. This association implies a protective effect against oxidative injury associated with the dietary lignans themselves, enterolactone, or some intermediate in this pathway. |
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