| CAS NO: | 91453-04-2 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 91453-04-2 |
| 别名 | 3-苯基-D5-2-丙烯酸-3-D1,3-Phenylacrylic acid-d6; β-Phenylacrylic acid-d6 |
| 分子式 | C9H2D6O2 |
| 分子量 | 154.2 |
| 溶解度 | DMSO : 250 mg/mL (1621.27 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cinnamic acid-d6 (3-Phenylacrylic acid-d6) is the deuterium labeled Cinnamic acid. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Liu L, et al. Cinnamic acid: a natural product with potential use in cancer intervention. Int J Cancer. 1995 Jul 28;62(3):345-50. |
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