| CAS NO: | 113942-30-6 |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 113942-30-6 |
| 别名 | 3,4-二氢-3-甲基-4-氧代咪唑并[5,1-D]-1,2,3,5-四嗪-8-甲酰胺酸 |
| Canonical SMILES | O=C(C(N=CN12)=C2N=NN(C)C1=O)O |
| 分子式 | C6H5N5O3 |
| 分子量 | 195.1 |
| 溶解度 | DMF: 2 mg/ml,DMSO: 3 mg/ml,Ethanol: insol,PBS (pH 7.2): insol |
| 储存条件 | -20буC |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Temozolomide acid is an active metabolite of the alkylating agent precursor temozolomide .1It is cytotoxic to TLX5 murine lymphoma cells in a concentration-dependent manner. Temozolomide acid is also a synthetic intermediate in the synthesis of temozolomide prodrugs with anticancer activity.2 1.Tsang, L.L.H., Farmer, P.B., Gescher, A., et al.Characterisation of urinary metabolites of temozolomide in humans and mice and evaluation of their cytotoxicityCancer Chemother. Pharmacol.26(6)429-436(1990) 2.Liu, D., Yang, J.-G., Cheng, J., et al.Synthesis and antitumor activity of 3-methyl-4-oxo-3,4-dihydroimidazo [5,1-d][1,2,3,5]tetrazine-8-carboxylates and -carboxamidesMolecules15(12)9427-9437(2010) |
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