| CAS NO: | 104227-86-3 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 104227-86-3 |
| 别名 | 泛昔洛韦USPRCA |
| Canonical SMILES | OCC(CCN1C=NC2=CN=C(N)N=C21)CO |
| 分子式 | C10H15N5O2 |
| 分子量 | 237.3 |
| 溶解度 | DMSO: slightly soluble,Methanol: slightly soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 6-Deoxypenciclovir is an inactive metabolite of the antiviral prodrug famciclovir .1,2It is formed from famciclovirviahydrolysis and is further metabolizedviaoxidation by aldehyde oxidase to the active metabolite penciclovir . 6-Deoxypenciclovir has been used in the synthesis of prodrug forms of penciclovir.3 1.Rashidi, M.R., Smith, J.A., Clarke, S.E., et al.In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liverDrug Metab. Dispos.25(7)805-813(1997) 2.Groth, A.D., Contreras, M.T., Kado-Fong, H.K., et al.In vitro cytotoxicity and antiviral efficacy against feline herpesvirus type 1 of famciclovir and its metabolitesVet. Ophthalmol.17(4)268-274(2014) 3.Kim, D.K., Lee, N., Ryu, D.H., et al.Synthesis and evaluation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines as potential prodrugs of penciclovirBioorg. Med. Chem.7(8)1715-1725(1999) |
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