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ABBV-167
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ABBV-167图片
CAS NO:1351456-78-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
ABBV-167 是一种 BCL-2 抑制剂 venetoclax 的磷酸盐前药。
Cas No.1351456-78-4
分子式C46H53ClN7O11PS
分子量978.45
溶解度DMSO : 100 mg/mL (102.20 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax.

[1]. Salem AH, et al. Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers. Mol Cancer Ther. 2021 Jun;20(6):999-1008.