| CAS NO: | 6453-67-4 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 6453-67-4 |
| 别名 | 焦脱镁叶绿酸Α甲酯,Pyropheophorbide-a methyl ester |
| Canonical SMILES | O=C1CC(C2=C1C(C)=C(C=C3C(CC)=C(C)C(C=C4C(C=C)=C(C)C(N4)=C5)=N3)N2)=C6[C@@H](CCC(OC)=O)[C@H](C)C5=N6 |
| 分子式 | C34H36N4O3 |
| 分子量 | 548.7 |
| 溶解度 | Chloroform: slightly soluble,Methanol: slightly soluble when heated |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pyropheophorbideamethyl ester is a photosensitizer and a derivative of chlorophylla.1It induces cell death in RIF-1 cells when used in combination with photodynamic therapy (PDT) at concentrations of 0.06 and 1 µM. Pyropheophorbideamethyl ester localizes to cell membranes and induces IL-1 receptor internalization and NF-κB activation following light exposure in HCT116 cells.2 1.Chen, Y., Zheng, X., Dobhal, M.P., et al.Methyl pyropheophorbide-a analogues: Potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacyJ. Med. Chem.48(11)3692-3695(2005) 2.Matroule, J.-Y., Bonizzi, G., MorliÈre, P., et al.Pyropheophorbide-a methyl ester-mediated photosensitization activates transcription factor NF-κB through the interleukin-1 receptor-dependent signaling pathwayJ. Biol. Chem.274(5)2988-3000(1999) |
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