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Cerberin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Cerberin图片
CAS NO:25633-33-4
包装:2.5mg
市场价:4046元

产品介绍
A cardiac glycoside with cytotoxic and cardiac modulatory activities
Cas No.25633-33-4
别名海果苷
Canonical SMILESO[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@](C(CO4)=CC4=O)([H])CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)C)O)OC)OC(C)=O)([H])CC3)C
分子式C32H48O9
分子量576.7
溶解度Chloroform: slightly soluble,Methanol: slightly soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cerberin is a cardiac glycoside that has been found inC. odollamand has cytotoxic and cardiac modulatory activities.1,2It is cytotoxic to KB and NCI H187 cancer cells (IC50s = 1.92 and 1.24 µg/ml).1Cerberin inhibits Na+/K+-ATPase, increasing intracellular sodium levels and action potential duration in cardiac cells.2

1.Laphookhieo, S., Cheenpracha, S., Karalai, C., et al.Cytotoxic cardenolide glycoside from the seeds of Cerbera odollamPhytochemistry65(4)507-510(2004) 2.Menezes, R.G., Usman, M.S., Hussain, S.A., et al.Cerbera odollam toxicity: A reviewJ. Forensic Leg. Med.58113-116(2018)