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N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide图片
CAS NO:560103-80-2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A derivative of INH1 with anticancer activity
Cas No.560103-80-2
别名N-[4-(2,4-二甲苯基)-2-噻唑基]-4-吡啶甲酰胺
Canonical SMILESCC1=C(C=CC(C)=C1)C2=CSC(NC(C3=CC=NC=C3)=O)=N2
分子式C17H15N3OS
分子量309.4
溶解度DMSO: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide is a derivative of INH1 with anticancer activity.1It is cytotoxic to MDA-MB-231, MDA-MB-488, HeLa, and K562 cells (IC50s = 1.1, 3.4, 1.6, and 1.2 µM, respectively).

1.Qiu, X.-L., Li, G., Wu, G., et al.Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analoguesJ. Med. Chem.52(6)1757-1767(2009)