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(+)-δ-Cadinene
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(+)-δ-Cadinene图片
CAS NO:483-76-1
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
A sesquiterpene with antimicrobial and anticancer activities
Cas No.483-76-1
别名Δ-杜松烯
Canonical SMILESCC([C@H]1[C@@]2([H])C(CCC(C)=C2)=C(CC1)C)C
分子式C15H24
分子量204.4
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(+)-δ-Cadinene is a sesquiterpene that has been found in upland cotton (G. hirsutum) and has antibacterial, insecticidal, and anticancer activities.1,2,3,4It is active againstS. pneumoniae(MIC = 31.25 µg/ml) and induces mortality inA. stephensi,A. aegypti, andC. quinquefasciatusthird instar larvae (LC50s = 8.23, 9.03, and 9.86 µg/ml, respectively).2,3(+)-δ-Cadinene (10, 50, and 100 µM) induces apoptosis in and inhibits proliferation of OVCAR-3 human ovarian cancer cells.4

1.Davis, G.D., and Essenberg, M.(+)-δ-Cadinene is a product of sesquiterpene cyclase activity in cottonPhytochemistry39(3)553-567(1995) 2.PÉrez-LÓpez, A., Cirio, A.T., Rivas-Galindo, V.M., et al.Activity against Streptococcus pneumoniae of the essential oil and δ-cadinene isolated from Schinus molle fruitJ. Essent. Oil Res.23(5)25-28(2011) 3.Govindarajan, M., Rajeswary, M., and Benelli, G.δ-Cadinene, calarene and δ-4-carene from Kadsura heteroclita essential oil as novel larvicides against malaria, dengue and filariasis mosquitoesComb. Chem. High Throughput Screen.19(7)565-571(2016) 4.Hui, L.-M., Zhao, G.-D., and Zhao, J.-J.δ-Cadinene inhibits the growth of ovarian cancer cells via caspase-dependent apoptosis and cell cycle arrestInt. J. Clin. Exp. Pathol.8(6)6046-6056(2015)