| 包装 | 价格(元) |
| 500 µg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| 别名 | CGA89317-13C,d3 |
| Canonical SMILES | ClC1=CC=CC(OC2=C(Cl)C=C(N=C(S[13C]([2H])([2H])[2H])N3)C3=C2)=C1Cl |
| 分子式 | C13[13C]H6D3Cl3N2OS |
| 分子量 | 363.7 |
| 溶解度 | Acetonitrile: soluble,DMSO: soluble,Methanol: soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Triclabendazole-13C-d3is intended for use as an internal standard for the quantification of triclabendazole by GC- or LC-MS. Triclabendazole is a benzimidazole anthelmintic.1It eliminates both immature and adult flukes in a sheep model ofF. hepaticainfection when administered at a dose of 10 mg/kg.2Triclabendazole (5 µM) also protects against glucose- or α-synuclein-induced apoptosis inS. cerevisiae viainhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.3 1.Shrifi, Y., Farahnak, A., Golestani, A., et al.Triclabendazole effect on protease enzyme activity in the excretory- secretory products of Fasciola hepatica in vitroIran. J. Parasitol.9(1)107-113(2014) 2.Smeal, M.G., and Hall, C.A.The activity of triclabendazole against immature and adult Fasciola hepatica infections in sheepAust. Vet. J.60(11)329-331(1983) 3.Lee, Y.J., Burlet, E., Wang, S., et al.Triclabendazole protects yeast and mammalian cells from oxidative stress: Identification of a potential neuroprotective compoundBiochem. Biophys. Res. Commun.414(1)205-208(2011) |
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