您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > FTX-6058 hydrochloride
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
FTX-6058 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FTX-6058 hydrochloride图片
CAS NO:2490676-19-0
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
(S)-Pociredir ((S)-FTX-6058) hydrochloride 是一种有效的、具有口服活性的胚胎外胚层发育 (EED) 抑制剂。
Cas No.2490676-19-0
别名(S)-FTX-6058 hydrochloride
分子式C22H19ClFN5O2
分子量439.87
溶解度DMSO : 125 mg/mL (284.17 mM; ultrasonic and warming and heat to 60°C)
储存条件4°C, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). FTX-6058 hydrochloride can induce HbF protein expression in cell and murine models. FTX-6058 hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].

FTX-6058 hydrochloride inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models[2].

[1]. Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021.