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(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid图片
CAS NO:34932-14-4
包装与价格：
包装价格(元)
25 µg电议
50 µg电议
100 µg电议

产品介绍
An oxylipin gut microbiota metabolite
Cas No.34932-14-4
Canonical SMILESCC/C=C\C/C=C\CC(O)CCCCCCCCC(O)=O
分子式C18H32O3
分子量296.5
溶解度Ethanol: 1 mg/ml
储存条件-20буC
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic acid is an oxylipin. It is produced from α-linolenic acid by the gut bacteriaL. plantarum.1(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic acid prevents increases in mRNA expression of the gene encoding SREBP-1c by the liver X receptor (LXR) agonist T0901317 in HepG2 cells. It reduces LPS-induced increases in nitric oxide (NO) production in RAW 264.7 macrophages when used at a concentration of 10 µM.2

1.Nanthirudjanar, T., Furumoto, H., Zheng, J., et al.Gut microbial fatty acid metabolites reduce triacylglycerol levels in hepatocytesLipids50(11)1093-1102(2015) 2.Yang, H.-E., Li, Y., Nishimura, A., et al.Synthesized enone fatty acids resembling metabolites from gut microbiota suppress macrophage-mediated inflammation in adipocytesMol. Nutr. Food Res.61(10)(2017)