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Etiocholanedione
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Etiocholanedione图片
CAS NO:1229-12-5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A neurosteroid
Cas No.1229-12-5
别名雄甾-3,17-二酮
Canonical SMILESC[C@@]12[C@]3([H])[C@](CC[C@]1([H])CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)(C(CC4)=O)C
分子式C19H28O2
分子量288.4
溶解度DMSO: soluble,Ethanol: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Etiocholanedione is a neurosteroid.1It inhibits glycine-induced chloride currents (IGly) in isolated rat hippocampal pyramidal neurons when used at a concentration of 50 µM. Etiocholanedione (0.1, 0.3, and 0.5 mM) also inhibits glucose exchange transport in isolated human erythrocytes.2

1.Bukanova, J.V., SoIntserva, I., and Kudova, E.Neurosteroids as selective inhibitors of glycine receptor activity: Structure-activity relationship study on endogenous androstanes and androstenesFront. Mol. Neurosci.1344(2020) 2.Lacko, L., Wittke, B., and Geck, P.Interaction of steroids with the transport system of glucose in human erythrocytesJ. Cell. Physiol.86 Suppl 2(3 Pt 2)673-680(1975)