| CAS NO: | 64936-82-9 |
| 包装: | 5mg |
| 市场价: | 4186元 |
| Cas No. | 64936-82-9 |
| 别名 | 甘氨石胆酸3-磺酸二钠盐 |
| Canonical SMILES | C[C@@]12[C@](CC[C@]2([H])[C@@H](CCC(NCC([O-])=O)=O)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)OS(=O)([O-])=O)([H])CC3)C.[Na+].[Na+] |
| 分子式 | C26H41NO7S • 2Na |
| 分子量 | 557.7 |
| 溶解度 | Methanol: slightly soluble,Water: slightly soluble |
| 储存条件 | Store at -20℃, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Glycolithocholic acid 3-sulfate is a metabolite of glycolithocholic acid .1It is formed from glycolithocholic acid by hepatocytes.2Glycolithocholic acid 3-sulfate (240 µmol/kg) induces cholestasis and increases biliary cholesterol secretion in rats.3Serum glycolithocholic acid 3-sulfate levels are increased in patients with cirrhosis, hepatitis, or cholestasis.4 1.Palmer, R.H.The formation of bile acid sulfates: A new pathway of bile acid metabolism in humansProc. Natl. Acad. Sci. USA58(3)1047-1050(1967) 2.Kirkpatrick, R.B., and Belsaas, R.A.Formation and secretion of glycolithocholate-3-sulfate in primary hepatocyte culturesJ. Lipid Res.26(12)1431-1437(1985) 3.Yousef, I.M., Tuchweber, B., Vonk, R.J., et al.Lithocholate cholestasis-sulfated glycolithocholate-induced intrahepatic cholestasis in ratsGastroenterology80(2)233-241(1981) 4.Demers, L.M., and Hepner, G.W.Levels of immunoreactive glycine-conjugated bile acids in health and hepatobiliary diseaseAm. J. Clin. Pathol.66(5)831-839(1976) |
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