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N-desethyl-N-methyl Vardenafil
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-desethyl-N-methyl Vardenafil图片
CAS NO:224785-87-9
包装与价格：
包装价格(元)
500 µg电议
1mg电议
5mg电议

产品介绍
A potential impurity found in commercial preparations of vardenafil
Cas No.224785-87-9
别名N-去乙基-N-甲基伐地那非
Canonical SMILESO=C1N=C(C2=C(OCC)C=CC(S(=O)(N3CCN(CC3)C)=O)=C2)NN4C(CCC)=NC(C)=C14
分子式C22H30N6O4S
分子量474.6
溶解度Acetonitrile: soluble,Methanol: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-desethyl-N-methyl Vardenafil is a potential impurity found in commercial preparations of the phosphodiesterase 5 (PDE5) inhibitor vardenafil .1It is also a PDE5 inhibitor (IC50= 2 nM).2

1.Subba Rao, D.V., Surendranath, K.V., Radhakrishnanand, P., et al.A stability indicating LC method for vardenafil HClChromatographia68(9)829-835(2008) 2.Haning, H., NiewÖhner, U., Schenke, T., et al.Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitorsBioorg. Med. Chem. Lett.15(17)3900-3907(2005)