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HG6-64-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
HG6-64-1图片
CAS NO:1315329-43-1
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
2mg电议
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
HG6-64-1是有效选择性的B-Raf抑制剂, 来自专利专利WO 2011090738 A2,化合物实例9 (XI-1)。在B-raf V600E转化的Ba/F3细胞中IC50值为0.09 μM。
Cas No.1315329-43-1
别名HMSL 10017-101-1
Canonical SMILESO=C(NC1=CC=C(CN2CCN(CC)CC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(/C=C/C4=CN=C(NC=C5)C5=C4OC)=C3
分子式C32H34F3N5O2
分子量577.64
溶解度DMSO: ≥ 100 mg/mL (173.12 mM); Water:< 0.1 mg/mL (insoluble)
储存条件4°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells. B-RafV600E|0.09 μM (IC50, in Ba/F3 cells)

[1]. WO 2011090738 A2