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GW284543
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GW284543图片
CAS NO:790186-68-4
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
GW284543 (UNC10225170) 是一个选择性的 MEK5 抑制剂。GW284543 (UNC10225170) 降低 pERK5,并下调内源性MYC 蛋白。
Cas No.790186-68-4
别名UNC10225170
Canonical SMILESCOC1=CC2=C(NC3=CC(OC4=CC=CC=C4)=CC=C3)C=CN=C2C=C1OC
分子式C23H20N2O3
分子量372.42
溶解度DMSO: 125 mg/mL (335.64 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 (UNC10225170) reduces pERK5, and decreases endogenous MYC protein[1]. MEK5

[1]. Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7.