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S961 acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装:5mg
市场价:2700元

产品介绍
S961acetate是一种高亲和力的胰岛素受体(insulinreceptor,IR)拮抗剂,对HIR-A,HIR-B和人胰岛素样生长因子I受体(HIGF-IR)的IC50分别为0.048,0.027和630nM。
分子式C213H301N55O72S2
分子量4864.18
溶解度DMSO : 12.5 mg/mL (2.57 mM; ) Water : 1.79 mg/mL (0.37 mM; ultrasonic and adjust pH to 8 with NaOH)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1].

S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively[1].

[1]. SchÄffer L, et al. A novel high-affinity peptide antagonist to the insulin receptor. Biochem Biophys Res Commun. 2008 Nov 14;376(2):380-3.