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CDK7/12-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CDK7/12-IN-1图片
CAS NO:2654075-94-0
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
CDK7/12-IN-1 是一种选择性 CDK7/12 抑制剂,对 CDK7 和 CDK 12 的 IC50 分别为 3 和 277 nM。抑制 CDK7 和 CDK12 是抑制肿瘤生长的有效策略。
Cas No.2654075-94-0
分子式C25H34N8O
分子量462.59
溶解度DMSO : 100 mg/mL (216.17 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CDK7/12-IN-1 is a selective CDK7/12 inhibitor with IC50s of 3 and 277 nM for CDK7 and CDK 12, respectively. CDK7 and CDK12 inhibition is an effective strategy to inhibit tumour growth[1].

[1]. Edward AINSCOW, et al. 4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol compounds and their therapeutic use. WO2021122745A1.