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6-O-Methyl Guanosine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
6-O-Methyl Guanosine图片
CAS NO:7803-88-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
6-O-Methyl Guanosine 是一种修饰的核苷。6-O-Methyl Guanosine (6-methylguanosine) 作用于恶性着色性干皮病细胞系,抑制集落形成。
Cas No.7803-88-5
别名6-O-甲基鸟苷
分子式C11H15N5O5
分子量297.27
溶解度DMSO : 130 mg/mL (437.31 mM; Need ultrasonic)|Water : 2 mg/mL (6.73 mM; Need ultrasonic and warming)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

6-O-Methyl Guanosine is a modified nucleoside[1]. 6-O-Methyl Guanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line[2].

[1]. Grasby JA, et al. The synthesis of oligoribonucleotides containing O6-methylguanosine: the role of conserved guanosine residues in hammerhead ribozyme cleavage. Nucleic Acids Res. 1993 Sep 25;21(19):4444-50.
[2]. Thielmann HW, et al. 6-Methylguanine and 6-methylguanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line but not in other xeroderma pigmentosum and normal human fibroblast strains after treatment with 1-(2-chloroethyl)-1-nitroso-3-(2-hydroxyethyl)-urea. J Cancer Res Clin Oncol. 1987;113(1):67-72.