| CAS NO: | 58207-19-5 |
| 包装 | 价格(元) |
| 1 g | 电议 |
| 5 g | 电议 |
| 10 g | 电议 |
| 25 g | 电议 |
| Cas No. | 58207-19-5 |
| 别名 | 盐酸克林霉素 |
| Canonical SMILES | O=C([C@@H]1C[C@H](CN1C)CCC)N[C@@H]([C@@]2([H])O[C@@H]([C@@H]([C@H]([C@H]2O)O)O)SC)[C@@H](Cl)C.Cl.O |
| 分子式 | C18H33ClN2O5S • HCl [H2O] |
| 分子量 | 479.5 |
| 溶解度 | DMF: 3 mg/ml,DMSO: 1 mg/ml,Ethanol: slightly,PBS (pH 7.2): 5 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Clindamycin is a lincosamide antibiotic.1,2It is active against Gram-positive bacteria, including various strains ofS. pneumoniae,S. viridans,S. aureus, andS. epidermidis(MICs = 0.002-0.1, 0.005-0.2, 0.04-1.6, and 0.1-0.2 µg/ml, respectively).1Clindamycin is also active against chloroquine-resistant and -sensitive strains ofP. falciparum(IC50s = 3.12 and 8.81 nM, respectively).2It inhibits bacterial protein synthesis by interacting with the 50S ribosome.1Clindamycin increases survival in a mouse model of a secondaryS. pneumoniaeinfection when administered at a dose of 15 mg/kg twice daily for seven days.3Formulations containing clindamycin have been used in the treatment of bacterial infections. 1.SpÍ?ek, J., and ?ezanka, T.Lincomycin, clindamycin and their applicationsAppl. Microbiol. Biotechnol.64(4)455-464(2004) 2.Dahl, E.L., and Rosenthal, P.J.Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplastAntimicrob. Agents Chemother.51(10)3485-3490(2007) 3.KarlstrÖm, Å., Boyd, K.L., English, B.K., et al.Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenzaJ. Infect. Dis.199(3)311-319(2009) |
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