包装 | 价格(元) |
1 g | 电议 |
5 g | 电议 |
10 g | 电议 |
25 g | 电议 |
Canonical SMILES | O=NN(CC)C(N)=O |
分子式 | C3H7N3O2• XH2O |
分子量 | 117.1 |
溶解度 | DMF: 15 mg/mL,DMSO: 20 mg/mL,Ethanol: 20 mg/mL,PBS (pH 7.2): 3 mg/mL |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 1-Ethyl-1-nitrosourea (ENU) is a DNA alkylating agent.1It increases the concentrations of O6-ethylguanine, N7-ethylguanine, N7-ethyladenine, and N3-ethyladenine in rat brain. ENU (80 mg/kg) is teratogenicin vivo, inducing tumor formation and paw malformations in rat pups when administered to pregnant rats.2 1.Goth, R., and Rajewsky, M.F.Persistence of O6-ethylguanine in rat-brain DNA: Correlation with nervous system-specific carcinogenesis by ethylnitrosoureaProc. Natl. Acad. Sci. USA71(3)639-643(1974) 2.Druckrey, H., Ivankovi?, S., and Preussmann, R.Teratogenic and carcinogenic effects in the offspring after single injection of ethylnitrosourea to pregnant ratsNature210(5043)1378-1379(1966) |