2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is
an endogenous cGAMP molecule found in mammalian cells, it binds to STING
with high affinity and is a potent inducer of interferon-β
(IFNβ). contains two distinct phosphodiester linkages, one between 2′-OH
of GMP and 5′-phosphate of AMP, and the other between 3′-OH of AMP and
5′-phosphate of GMP. 2',3'-cGAMP is produced in mammalian cells in
response to DNA in the cytoplasm and binds to STING with a high affinity
and is a potent inducer of interferon-β (IFNβ).
纯度:≥98%