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Metformin D6 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Metformin D6 hydrochloride图片
CAS NO:1185166-01-1
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
MetforminD6hydrochloride是Metforminhydrochloride的一种氘代化合物。Metforminhydrochloride抑制肝脏中的线粒体呼吸链,导致AMPK活化,增强胰岛素敏感性,可用于2型糖尿病的研究。Metforminhydrochloride可以透过血脑屏障,诱导自噬(autophagy)。
Cas No.1185166-01-1
别名二甲双胍盐酸,1,1-Dimethylbiguanide-d6 hydrochloride
Canonical SMILESNC(NC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=N)=N.[H]Cl
分子式C4H6D6ClN5
分子量171.66
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Metformin D6 hydrochloride is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1].

[1]. Soraya H, et al. Acute treatment with metformin improves cardiac function following NSC 37745 induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.