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Erucic acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Erucic acid图片
CAS NO:112-86-7
包装与价格：
包装价格(元)
Free Sample (0.1-0.5mg)电议
10mM (in 1mL DMSO)电议
100mg电议
200mg电议
500mg电议

产品介绍
Erucic acid 是一种单不饱和脂肪酸 (MUFA)，从萝卜的种子中分离出来的。Erucic acid 很容易地穿过血脑屏障 (BBB)，它可以使大脑中长链脂肪酸的积累正常化。Erucic acid 可以改善认知障碍并有效预防痴呆。
Cas No.112-86-7
别名芥酸
Canonical SMILESCCCCCCCC/C=C\CCCCCCCCCCCC(O)=O
分子式C22H42O2
分子量338.57
溶解度DMSO: ≥ 100 mg/mL (295.36 mM); Water:< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia[1].

Erucic acid (oral administration; 3 mg/kg) enhances the phosphorylation level of PI3K, PKCζ, ERK, CREB and Akt in the hippocampus compared with that in the vehicle-treated control group[1]. Animal Model: Normal naÏve mice[1]

[1]. Kim E, et al. The memory-enhancing effect of erucic acid on scopolamine-induced cognitive impairment in mice. Pharmacol Biochem Behav. 2016 Mar;142:85-90.