| CAS NO: | 305-01-1 |
| 包装: | 100mg |
| 市场价: | 450元 |
Esculetin 是一种主要从水曲柳 (Fraxinus rhynchophylla) 的树皮中提取的活性成分。 Esculetin 通过抑制 PI3K/Akt 途径来抑制血小板衍生生长因子 (PDGF) 诱导的气道平滑肌细胞 (ASMCs) 表型转换。Esculetin 具有抗氧化，抗炎和抗肿瘤的作用。
| Cas No. | 305-01-1 |
| 别名 | 秦皮乙素 |
| Canonical SMILES | O=C1C=CC2=CC(O)=C(O)C=C2O1 |
| 分子式 | C9H6O4 |
| 分子量 | 178.14 |
| 溶解度 | DMSO: 250 mg/mL (1403.39 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Esculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities[1]. [1]. Xie C, et al. Esculetin regulates the phenotype switching of airway smooth muscle cells. Phytother Res. 2019 Aug 21. |
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