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NVP-QAV-572
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NVP-QAV-572图片
CAS NO:957209-68-6
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Nav1.7-IN-2 是一种有效的 PI3K 抑制剂,IC50 为 10 nM,详细信息可参考专利文献US7998990B2 中的化合物 Example 8。
Cas No.957209-68-6
别名N-[2-[2-(2-氟乙基)-2H-四唑-5-基]乙基]-N'-[5-[3-氟-4-(甲基磺酰基)苯基]-4-甲基-2-噻唑基]脲
Canonical SMILESO=C(NC1=NC(C)=C(C2=CC=C(S(=O)(C)=O)C(F)=C2)S1)NCCC3=NN(CCF)N=N3
分子式C17H19F2N7O3S2
分子量471.5
溶解度DMSO: 125 mg/mL (265.11 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NVP-QAV-572 is a PI3K inhibitor extracted from patent US7998990B2, Compound Example 8, has an IC50 of 10 nM. PI3K|10 nM (IC50)

NVP-QAV-572 (Example 8) is useful in the treatment of conditions which are mediated by the activation of the Pi3 kinase enzymes, particularly inflammatory or allergic conditions[1].

[1]. Emma Budd, et al. 5-phenyl-thiazol-2-yl-urea derivatives and use as PI3 kinase inhibitors. US 7998990 B2.