Hymecromone sodium (4-Methylumbelliferone sodium) is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM. 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor. The activation of HAS2 and the over-production of HA are existed in many metastatic tumor cell lines. Increased synthesis of HA is often associated with increased metastatic potential and invasivity in tumor cells. 4-Methylumbelliferone (MU), an inhibitor of HA synthesis, has been studied as a potential anti-tumor drug on account of inhibiting the growth of primary tumors and distant metastasis of tumor cells.
纯度:≥98%
CAS:5980-33-6