CAS NO: | 1638211-04-7 |
包装: | 1mg |
市场价: | 2070元 |
Cas No. | 1638211-04-7 |
分子式 | C21H16F3N3O2 |
分子量 | 399.37 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1[1]. ML303 (20 μM, 6 h) treatment restore IFN-β mRNA levels in MDCK cells[1]. [1]. Patnaik S, et al. Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists. Bioorg Med Chem Lett. 2019 May 1;29(9):1113-1119. |