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PBP 10(trifluoroacetate salt)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
PBP 10(trifluoroacetate salt)图片
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A peptide FPR2 antagonist
Canonical SMILESCCN(C1=CC([O+]=C2C=C(C=CC2=C3C4=C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)CCCNC(N)=N)=O)=O)CCCCN)=O)C(C)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)C=CC=C4)N(CC)CC)=C3C=C1)CC.OC(C(F)(F)F)=O
分子式C84H127N24O15• XCF3COOH
分子量1713.1
溶解度DMSO: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

PBP 10 is a peptide formyl peptide receptor 2 (FPR2) antagonist (IC50= 60 nM).1It is active againstE. coli,P. aeruginosa, andS. pneumoniaewhen used at concentrations ranging from 0.1 to 100 µM.2

1.Skovbakke, S.L., Holdfeldt, A., Nielsen, C., et al.Combining elements from two antagonists of formyl peptide receptor 2 generates more potent peptidomimetic antagonistsJ. Med. Chem.60(16)6991-6997(2017) 2.Bucki, R., Pastore, J.J., Randhawa, P., et al.Antibacterial activities of rhodamine B-conjugated gelsolin-derived peptides compared to those of the antimicrobial peptides cathelicidin LL37, magainin II, and melittinAntimicrob. Agents Chemother.48(5)1526-1533(2004)