您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Aniline-d5
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Aniline-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Aniline-d5图片
CAS NO:4165-61-1
包装与价格:
包装价格(元)
250mg电议
500mg电议
1 g电议

产品介绍
An internal standard for the quantification of aniline
Cas No.4165-61-1
别名苯胺-2,3,4,5,6-d5
Canonical SMILES[2H]C1=C(N)C([2H])=C([2H])C([2H])=C1[2H]
分子式C6H2D5N
分子量98.2
溶解度DMF: 15 mg/ml,DMSO: 10 mg/ml,Ethanol: 3 mg/ml,PBS (pH 7.2): 5 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Aniline-d5intended for use as an internal standard for the quantification of aniline by GC- or LC-MS. Aniline is an aromatic amine that has been used as a starting material in the synthesis of a wide variety of precursors to dyes and pigments, rubber processing chemicals, and agricultural chemicals.1It increases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) and decreases the levels of glutathione and catalase, as well as the activity of superoxide dismutase (SOD), in primary rat hepatocytes when used at concentrations of 5 and 10 µg/ml.2Aniline (0.3 and 0.6% of the diet) induces splenic sarcomas in rats and is neurotoxic to rats when administered at doses of 750 and 1,000 mg/kg.3,4Formulations containing aniline have been used in the synthesis of pharmaceuticals.

1.Kahl, T., SchrÖder, K.-Q., Lawrence, F.R., et al.Aniline3465-478(2011) 2.Wang, Y., Gao, H., Na, X.-L., et al.Aniline induces oxidative stress and apoptosis of primary cultured hepatocytesInt. J. Environ. Res. Public Health13(12)1188(2016) 3.Goodman, D.G., Ward, J.M., and Reichardt, W.D.Splenic fibrosis and sarcomas in F344 rats fed diets containing aniline hydrochloride, p-chloroaniline, azobenzene, o-toluidine hydrochloride, 4,4’-sulfonyldianiline, or D & C red No. 9J. Natl. Cancer Inst.73(1)265-273(2019) 4.Okazaki, Y., Yamashita, K., Sudo, M., et al.Neurotoxicity induced by a single oral dose of aniline in ratsJ. Vet. Med. Sci.63(5)539-546(2001)