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L-Leu-AMC(hydrochloride)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
L-Leu-AMC(hydrochloride)图片
CAS NO:62480-44-8
包装与价格：
包装价格(元)
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride 是 LAP3（亮氨酸氨基肽酶）的亮蓝色荧光肽基底物。
Cas No.62480-44-8
别名L-亮氨酰7-氨基-4-甲基香豆素盐酸盐,Leu-AMC hydrochloride
Canonical SMILESCC(C1=CC=C(NC([C@@H](N)CC(C)C)=O)C=C1O2)=CC2=O.Cl
分子式C16H20N2O3·HCl
分子量324.8
溶解度DMF: 25 mg/ml,DMSO: 25 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase.1Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

1.Izquierdo, M., Lin, D., O’Neill, S., et al.Development of a high-throughput screening assay to identify inhibitors of the major M17-leucyl aminopeptidase from Trypanosoma cruzi using rapidfire mass spectrometrySLAS Discov.25(9)1064-1071(2020)