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Isorhoifolin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Isorhoifolin图片
CAS NO:552-57-8
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Isorhoifolin 是一种来自 periploca nigrescens 叶子的类黄酮苷。
Cas No.552-57-8
别名异野漆树苷
Canonical SMILESO=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)C=C2OC(C5=CC=C(C=C5)O)=C1
分子式C27H30O14
分子量578.5
溶解度DMSO: soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Isorhoifolin is a flavonoid glycoside and an aglycone form of apigenin that has been found inM. longifoliaand has diverse biological activities.1,2,3It inhibits matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-13 (IC50s = 0.33, 2.45, and 0.22 µM, respectively).1Isorhoifolin has antimutagenic properties in theE. coliWP2 tryptophan reverse mutation assay when used at a concentration of 2 µM.2It is active againstS. aureusandP. aeruginosa, but notE. coliorC. albicans, in agar diffusion assays when used at a concentration of 140 µg/ml.3

1.Crasci, L., Basile, L., Panico, A., et al.Correlating in vitro target-oriented screening and docking: Inhibition of matrix metalloproteinases activities by flavonoidsPlanta Med.83(11)901-911(2017) 2.Baris, O., Karadayi, M., Yanmis, D., et al.Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potentials by using the E. coli WP2 test systemJ. Food. Sci.76(9)T212-T217(2011) 3.Abu-Gharbieh, E., and Shehab, N.G.Therapeutic potentials of Crataegus azarolus var. eu- azarolus Maire leaves and its isolated compoundsBMC Complement. Altern. Med.17(1)218(2017)