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Safflower Red
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Safflower Red图片
CAS NO:36338-96-2
包装与价格：
包装价格(元)
5 g电议
10 g电议
25 g电议
50 g电议

产品介绍
A red pigment with diverse biological activities
Cas No.36338-96-2
别名红花黄色素
Canonical SMILESO[C@](C(O)=C1C(/C=C/C(C=C2)=CC=C2O)=O)([C@]([C@@H]([C@H]3O)O)([H])O[C@@H]([C@H]3O)CO)C(/C(C1=O)=C\C(C(C(C(/C=C/C(C=C4)=CC=C4O)=O)=C5O)=O)=C([C@]5([C@]([C@@H]([C@H]6O)O)([H])O[C@@H]([C@H]6O)CO)O)O)=O
分子式C43H42O22
分子量910.8
溶解度DMF: 1 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Safflower red is a polyketide synthase-derived quinochalcone glucoside red pigment originally isolated fromC. tinctoriusthat has diverse biological activities.1,2,3,4Safflower red (100 and 200 µM) inhibits LPS-induced decreases in collagen II and aggrecan levels and reverses LPS-induced increases inTNFexpression in isolated rat nucleus pulposus cells.3It reverses decreases in serum glutathione (GSH) and superoxide dismutase (SOD) levels and increases in serum malondialdehyde (MDA) levels, as well as decreases infarct area and brain edema induced by middle cerebral artery occlusion (MCAO), in a rat model of cerebral ischemia-reperfusion injury when administered at a dose of 40 mg/kg.4Formulations containing safflower red have been used in the food, cosmetics, and clothing industries.

1.Shinozaki, J., Kenmoku, H., Nihei, K., et al.Cloning and functional analysis of three chalcone synthases from the flowers of safflowers Carthamus tinctoriusNat. Prod. Commun.11(6)787-790(2016) 2.Kazuma, K., Takahashi, T., Sato, K., et al.Quinochalcones and flavonoids from fresh florets in different cultivars of Carthamus tinctorius LBiosci. Biotechnol. Biochem.64(8)1588-1599(2000) 3.Chen, B., Wang, H.-T., Yu, B., et al.Carthamin yellow inhibits matrix degradation and inflammation induced by LPS in the intervertebral disc via suppression of MAPK pathway activationExp. Ther. Med.14(2)1614-1620(2017) 4.Guo, H., Zhu, L., Tang, P., et al.Carthamin yellow improves cerebral ischemia?reperfusion injury by attenuating inflammation and ferroptosis in ratsInt. J. Mol. Med.47(4)52(2021)