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Glyphosate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glyphosate图片
CAS NO:1071-83-6
包装:500mg
市场价:450元

产品介绍
Glyphosate是一种氨基酸甘氨酸的除草衍生物。Glyphosate靶向并阻断一种在动物中没有发现的植物代谢途径,莽草酸途径,这是植物合成芳香氨基酸所必需的。
Cas No.1071-83-6
别名草甘膦
Canonical SMILESO=C(O)CNCP(O)(O)=O
分子式C3H8NO5P
分子量169.07
溶解度Water: 13.89 mg/mL (82.16 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants[1].

Glyphosate is a high-efficiency, low-toxicity, broad-spectrum herbicide. The residues of glyphosate-based herbicides are frequent pollutants in the environment. Glyphosate exposure could interfere with mouse oocyte maturation by generating oxidative stress and early apoptosis.Glyphosate induces early apoptosis and autophagy in mouse oocytes[2].

[1]. Greim H, et al. Evaluation of carcinogenic potential of the herbicide glyphosate, drawing on tumor incidence data from fourteen chronic/carcinogenicity rodent studies. Crit Rev Toxicol. 2015;45(3):185-208. [2]. Zhang JW, et al The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. 2019 Dec;237:124435.