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CFTR corrector 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CFTR corrector 1图片
CAS NO:2216712-66-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
CFTR 校正剂 1 (VX-445, Compound 1) 是囊性纤维化跨膜电导调节剂 (CFTR) 的调节剂。
Cas No.2216712-66-0
别名VX-445
Canonical SMILESCC1(C)C[C@H](C)CN1C2=C(C(NS(C3=CN(C)N=C3C)(=O)=O)=O)C=CC(N4C=CC(OCC(C)(C(F)(F)F)C)=N4)=N2
分子式C26H34F3N7O4S
分子量597.65
溶解度DMSO: 125 mg/mL (209.15 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CFTR corrector 1 (compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). CFTR corrector 1 (compound 1) facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface[1]. CFTR[1].

[1]. Alexander Russell Abela, et al. MODULATOR OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR , PHARMACEUTICAL COMPOSITIONS , METHODS OF TREATMENT , AND PROCESS FOR MAKING THE MODULATOR. US 20180162839 A1.